Terho E O
Enheten för klinisk allergologi, Abo universitet.
Nord Med. 1994;109(8-9):238-41.
The diagnosis of food allergy is one of the most difficult tasks in allergology, as only some of the hypersensitive reactions are of allergic origin, and even those that are allergic are not always IgE mediated. On the basis of the history, an attempt is made to determine the type of symptoms and the degree of severity, and identify eliciting foodstuffs. As diagnostic aids, prick tests and allergen-specific IgE tests have their limitations, since only IgE-mediated allergies can be identified. Diagnosis is based upon dietary elimination and subsequent challenge. Challenge must be repeated several times and a placebo controlled double blind approach be adopted. No foodstuff should be eliminated from the diet solely on the basis of prick test results.
食物过敏的诊断是过敏学中最困难的任务之一，因为只有一些超敏反应是由过敏引起的，而且即使是过敏反应也并非总是由IgE介导。根据病史，尝试确定症状类型和严重程度，并识别引发过敏的食物。作为诊断辅助手段，点刺试验和过敏原特异性IgE检测有其局限性，因为它们只能识别由IgE介导的过敏。诊断基于饮食排除和随后的激发试验。激发试验必须重复多次，并采用安慰剂对照双盲方法。不应仅根据点刺试验结果就从饮食中排除任何食物。
