Holditch-Davis D, Edwards L J, Wigger M C
School of Nursing, University of North Carolina at Chapel Hill.
Nurs Res. 1994 Sep-Oct;43(5):293-300.
The development of pathologic apnea, respiratory pauses, and periodic respiration was examined in 71 high-risk preterm infants, observed weekly. Respiration was recorded every 10 seconds; apnea length and periodic respiration were scored from a tape. All subjects had respiratory pauses, and 36 had pathologic apnea. The mean length of respiratory pauses was longer in quiet sleep, and the frequency of respiratory pauses was greater in active sleep. The mean length of respiratory pauses and probability of pathologic apnea in both sleep states and frequency of pauses in quiet sleep decreased with age. Sex, theophylline treatment, race, and length of mechanical ventilation affected the developmental trajectories of some apnea variables. Apnea in preterm infants cannot be considered a unitary phenomenon.
对71名高危早产儿进行了病理性呼吸暂停、呼吸暂停及周期性呼吸发展情况的检查，每周观察一次。每10秒记录一次呼吸；根据录像带对呼吸暂停时长和周期性呼吸进行评分。所有受试者均有呼吸暂停，36例有病理性呼吸暂停。安静睡眠时呼吸暂停的平均时长更长，活跃睡眠时呼吸暂停的频率更高。两种睡眠状态下呼吸暂停的平均时长、病理性呼吸暂停的概率以及安静睡眠时呼吸暂停的频率均随年龄增长而降低。性别、茶碱治疗、种族及机械通气时长影响了部分呼吸暂停变量的发展轨迹。早产儿的呼吸暂停不能被视为一种单一现象。
