Gould K, Gates M L, Miaskowski C
Stanford University Medical Center Bone Marrow Transplant Program, CA.
Oncol Nurs Forum. 1994 Jun;21(5):835-40.
PURPOSE/OBJECTIVES: To review the Breast Cancer Prevention Trial, which is testing tamoxifen as a chemoprevention agent.
Published articles and books; National Surgical Adjuvant Breast Project protocols.
Because tamoxifen has proven to be an effective hormonal agent in the treatment of all stages of breast cancer and because it has a low side effect rate, a national study is under way to determine its effects as a breast cancer preventive agent.
Results of this double-blind, placebo-controlled study will be available at the study's completion in 1997.
Providing patients with education, informed consent assistance, and help in adjusting to the drug's side effects and influences on quality of life.
目的/目标：回顾乳腺癌预防试验，该试验正在测试他莫昔芬作为一种化学预防剂的效果。
已发表的文章和书籍；国家外科辅助乳腺项目方案。
由于他莫昔芬已被证明是治疗各阶段乳腺癌的有效激素药物，且副作用发生率较低，因此正在进行一项全国性研究以确定其作为乳腺癌预防剂的效果。
这项双盲、安慰剂对照研究的结果将于1997年研究结束时得出。
为患者提供教育、知情同意协助，并帮助他们适应药物的副作用及其对生活质量的影响。
