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[三磷酸腺苷在急救服务中的临床实用性及疗效]

[The clinical usefulness and efficacy of adenosine triphosphate in an emergency service].

作者信息

Roig García J J, Jiménez Murillo L M, Clemente Millán M J, González Barranco J M, Segura Saint-Gerons J, Montero Pérez F J

机构信息

Unidad Funcional de Urgencias, Hospital Universitario Reina Sofía, Córdoba.

出版信息

Rev Clin Esp. 1994 Aug;194(8):594-8.

PMID:7938837
Abstract

We studied 89 patients diagnosed in our emergency department of paroxysmal supraventricular tachycardia, to describe the efficacy and safety of intravenous adenosine triphosphate (ATP) in their treatment. All received a first bolus of 10 mg of ATP and if no electrical response was observed, a second dose of 20 mg. This treatment was successful in 91% of the patients, lasting of 26.9 seconds to resolve the episode, and in the 53% of the patients with the first dose. In 9% of the patients ATP did not resolve the episode but allowed to diagnose it, which in five patients was atrial flutter, in 2 Wolff-Parkinson-White syndrome and in one atrial fibrillation. Adverse effects appeared in 25.6% of the cases, being in all transitory and banal. ATP is a very effective and safe drug for the treatment of patients with PSVT.

摘要

我们对在我院急诊科诊断为阵发性室上性心动过速的89例患者进行了研究,以描述静脉注射三磷酸腺苷(ATP)治疗该病的有效性和安全性。所有患者均首先静脉推注10mg ATP,若未观察到电反应,则给予第二剂20mg。该治疗在91%的患者中取得成功,发作缓解持续时间为26.9秒,53%的患者使用第一剂即成功。9%的患者使用ATP后发作未缓解,但有助于明确诊断,其中5例为心房扑动,2例为预激综合征,1例为心房颤动。25.6%的病例出现不良反应,均为短暂且轻微的。ATP是治疗阵发性室上性心动过速患者的一种非常有效且安全的药物。

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