Wendling D, Risold J C
Service de rhumatologie, hôpital Jean-Minjoz, CHU, Besançon, France.
Rev Med Interne. 1994;15(7):448-51. doi: 10.1016/s0248-8663(05)81468-7.
Vascular involvement is seldom reported in ankylosing spondylitis (AS). In this study, microcirculation was evaluated by nailfold capillaroscopy in 32 defined AS patients compared to a control group (C) of 14 sciatica. Capillary findings were divided into five groups: normal, minor dystrophies, edema, microangiopathy, stagnation. Capillaroscopic abnormalities were more frequent in SA as compared to C, for edema (40% vs 7%) and microangiopathy (15% vs 0%). P = 0.01. There were neither clinical nor biological differences between AS patients with and without microangiopathy. Capillaroscopy abnormalities seem frequent in AS and may be secondary to an immune complex mechanism.
血管受累在强直性脊柱炎(AS)中鲜有报道。在本研究中,通过甲襞毛细血管镜检查对32例确诊的AS患者的微循环进行了评估,并与14例坐骨神经痛患者组成的对照组(C)进行比较。毛细血管检查结果分为五组:正常、轻度营养不良、水肿、微血管病、停滞。与对照组相比,AS患者的毛细血管镜异常更为常见,水肿(40% 对7%)和微血管病(15% 对0%)。P = 0.01。有无微血管病的AS患者在临床和生物学方面均无差异。毛细血管镜异常在AS中似乎很常见,可能继发于免疫复合物机制。