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[甲襞毛细血管镜检查与强直性脊柱炎:异常的发生率,但缺乏诊断和预后价值]

[Nailfold capillaroscopy and ankylosing spondylarthritis: incidence of anomalies, but absence of diagnostic and prognostic value].

作者信息

Wendling D, Risold J C

机构信息

Service de rhumatologie, hôpital Jean-Minjoz, CHU, Besançon, France.

出版信息

Rev Med Interne. 1994;15(7):448-51. doi: 10.1016/s0248-8663(05)81468-7.

Abstract

Vascular involvement is seldom reported in ankylosing spondylitis (AS). In this study, microcirculation was evaluated by nailfold capillaroscopy in 32 defined AS patients compared to a control group (C) of 14 sciatica. Capillary findings were divided into five groups: normal, minor dystrophies, edema, microangiopathy, stagnation. Capillaroscopic abnormalities were more frequent in SA as compared to C, for edema (40% vs 7%) and microangiopathy (15% vs 0%). P = 0.01. There were neither clinical nor biological differences between AS patients with and without microangiopathy. Capillaroscopy abnormalities seem frequent in AS and may be secondary to an immune complex mechanism.

摘要

血管受累在强直性脊柱炎(AS)中鲜有报道。在本研究中,通过甲襞毛细血管镜检查对32例确诊的AS患者的微循环进行了评估,并与14例坐骨神经痛患者组成的对照组(C)进行比较。毛细血管检查结果分为五组:正常、轻度营养不良、水肿、微血管病、停滞。与对照组相比,AS患者的毛细血管镜异常更为常见,水肿(40% 对7%)和微血管病(15% 对0%)。P = 0.01。有无微血管病的AS患者在临床和生物学方面均无差异。毛细血管镜异常在AS中似乎很常见,可能继发于免疫复合物机制。

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