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一种用于量化嗅觉缺陷的新型临床嗅觉测试。

A new clinical olfactory test to quantify olfactory deficiencies.

作者信息

Eloit C, Trotier D

机构信息

ENT Clinic, Hôpital Lariboisière, Paris, France.

出版信息

Rhinology. 1994 Jun;32(2):57-61.

PMID:7939140
Abstract

We have recently developed a computer-assisted olfactory test to measure detection thresholds for five pure odorants. The reference group consisted of 30 subjects without olfactory complaints. Statistical analysis was carried out to identify a statistical criterion for determining olfactory deficiencies. This criterion was applied to 54 subjects suspected to have an olfactory deficiency, either on the basis of their subjective complaints or on clinical examinations (e.g. scanner radiography, endoscopic investigations, rhinomanometric measurements). Nine aetiological groups were screened: trauma, nasal polyposis, nasal obstruction, allergic rhinitis, post-influenza, post-anaesthesia, endocrine dysfunction, hereditary hyposmia, and subjective olfactory loss without a clear aetiology. In each group, this method allowed us to discriminate between deficient and non-deficient patients, and the olfactory deficit could be quantified. This rapid procedure was well-accepted by all subjects and gave reproducible quantitative results. It can provide useful information about the relationship between olfactory acuity and a given aetiologic category.

摘要

我们最近开发了一种计算机辅助嗅觉测试,以测量五种纯气味剂的检测阈值。参照组由30名无嗅觉问题的受试者组成。进行了统计分析,以确定用于判定嗅觉缺陷的统计标准。该标准应用于54名疑似有嗅觉缺陷的受试者,这些受试者要么基于主观主诉,要么基于临床检查(如扫描放射成像、内窥镜检查、鼻阻力测量)。筛查了九个病因组:创伤、鼻息肉病、鼻阻塞、过敏性鼻炎、流感后、麻醉后、内分泌功能障碍、遗传性嗅觉减退以及无明确病因的主观性嗅觉丧失。在每组中,该方法使我们能够区分有缺陷和无缺陷的患者,并且可以对嗅觉缺陷进行量化。这种快速的程序得到了所有受试者的认可,并给出了可重复的定量结果。它可以提供有关嗅觉敏锐度与特定病因类别之间关系的有用信息。

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