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鼻减充血剂羟甲唑啉的一种新给药形式:健康个体窦口通畅性变化的研究

A new administration form of the nasal decongestant oxymetazoline: a study on the change of ostial patency in healthy individuals.

作者信息

Jannert M, Fryksmark U, Ackerhans M, Nilson K

机构信息

Department of Otorhinolaryngology, University of Lund, Malmö General Hospital, Sweden.

出版信息

Rhinology. 1994 Jun;32(2):78-80.

PMID:7939146
Abstract

A new administration form of the nasal decongestant oxymetazoline and the effect on patency of the maxillary ostium was investigated in five healthy volunteers. Registration and comparison of the equivalent diameter after administration of placebo spray and oxymetazoline spray, placebo solution and oxymetazoline solution were performed. It is our impression that administration of solution with the new spring-bellows container compared to spray oxymetazoline, is a more effective way of increasing the equivalent diameter of the maxillary ostium.

摘要

在五名健康志愿者中研究了鼻减充血剂羟甲唑啉的一种新给药形式及其对上颌窦口通畅度的影响。对安慰剂喷雾和羟甲唑啉喷雾、安慰剂溶液和羟甲唑啉溶液给药后的等效直径进行了记录和比较。我们的印象是,与喷雾型羟甲唑啉相比,使用新型弹簧风箱容器的溶液给药是增加上颌窦口等效直径的更有效方法。

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