通过内镜超声对胃溃疡愈合进行序贯观察。

Sequential observation of gastric ulcer healing by endoscopic ultrasonography.

作者信息

Yoshikane H, Tsukamoto Y, Niwa Y, Goto H, Hase S

机构信息

Second Dept. of Internal Medicine, Nagoya University School of Medicine, Japan.

出版信息

Scand J Gastroenterol. 1994 Jul;29(7):665-70. doi: 10.3109/00365529409092490.

DOI:10.3109/00365529409092490

PMID:7939406

Abstract

BACKGROUND

The relationship between superficial findings and the inner structure of gastric ulcers is unclear. The present study was undertaken to clarify the relationship between them.

METHODS

In the first study, 43 patients with active gastric ulcers were examined by endoscopic ultrasonography (EUS) in each stage of Sakita's endoscopic classification. In the second study, 16 patients with gastric ulcer scars were examined by EUS in both S1 stage and S2 stage.

RESULTS

Ulcer area, ulcer length, thickness of the ulcer base, and diameter of the crater differed significantly in each endoscopic stage. Ulcer area, ulcer length, and thickness of the ulcer base differed significantly even between S1 stage and S2 stage. Mean ulcer area in S1 stage was 96.9 mm2; this shows that the ulcer scar in S1 stage is incomplete with regard to tissue contraction. Although ulcer area in S2 stage had shrunk significantly compared with that in S1 stage, it still remained 53.3 mm2. This implies that the risk of local recurrence remains even in S2 stage.

CONCLUSIONS

Sequential observation by EUS showed that the healing of the ulcer surface strongly reflected the healing within the ulcers.

摘要

背景

胃溃疡的表面表现与内部结构之间的关系尚不清楚。本研究旨在阐明它们之间的关系。

方法

在第一项研究中，对43例活动期胃溃疡患者在酒田内镜分类的每个阶段进行了超声内镜检查（EUS）。在第二项研究中，对16例胃溃疡瘢痕患者在S1期和S2期均进行了EUS检查。

结果

溃疡面积、溃疡长度、溃疡基底厚度和溃疡坑直径在各内镜阶段存在显著差异。即使在S1期和S2期之间，溃疡面积、溃疡长度和溃疡基底厚度也存在显著差异。S1期的平均溃疡面积为96.9平方毫米；这表明S1期的溃疡瘢痕在组织收缩方面是不完全的。虽然S2期的溃疡面积与S1期相比显著缩小，但仍为53.3平方毫米。这意味着即使在S2期，局部复发的风险仍然存在。