Sparwasser C, Drescher P, Pust R A, Madsen P O
Urology Section, VA Hospital, Madison, WI.
Scand J Urol Nephrol Suppl. 1994;157:107-12.
A follow up study of 603 patients with chronic erectile failure was carried out concerning the long term effects of intracavernous injection therapy with papaverine/phentolamine (n = 172 evaluable) and venous surgery (n = 134 evaluable). Injection therapy was effective in 95.8% of injections. Side effects included prolonged erections in 0.15% of injections and fibrotic palpable indurations in 3.4%. Acceptance of therapy was high among patients and their partners and improvement of self image or partnership was reported in 77.8% and 79.5% respectively. Results of venous surgery were not satisfactory. Only 19.4% of patients achieved sufficient spontaneous erections and 35.1% needed adjuvant injections. Spongiosolysis yielded better results. Patients with neurological impairment, diabetes mellitus, postoperative onset of erectile dysfunction and age above 40 years showed poorer surgical results. Venous surgery should only be offered to a highly selected group of patients.
对603例慢性勃起功能障碍患者进行了一项随访研究，内容涉及罂粟碱/酚妥拉明海绵体内注射疗法（172例可评估）和静脉手术（134例可评估）的长期效果。注射疗法在95.8%的注射中有效。副作用包括0.15%的注射出现阴茎异常勃起，3.4%出现可触及的纤维化硬结。患者及其伴侣对治疗的接受度很高，分别有77.8%和79.5%的患者报告自我形象或伴侣关系得到改善。静脉手术的结果并不令人满意。只有19.4%的患者能够实现充分的自然勃起，35.1%的患者需要辅助注射。海绵体松解术效果更好。存在神经功能损害、糖尿病、勃起功能障碍术后发病以及年龄在40岁以上的患者手术效果较差。静脉手术仅应提供给经过严格筛选的患者群体。
