Patel N H
Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210-3399.
Science. 1994 Oct 28;266(5185):581-90. doi: 10.1126/science.7939712.
Rapid advances have been made in the understanding of the genetic basis of development and pattern formation in a variety of model systems. By examining the extent to which these developmental systems are conserved or altered between different organisms, insight can be gained into the evolutionary events that have generated the diversity of organisms around us. The molecular and genetic basis of early pattern formation in Drosophila melanogaster has been particularly well studied, and comparisons to other insects have revealed conservation of some aspects of development, as well as differences that may explain variations in early patterning events.
在理解各种模式生物发育和模式形成的遗传基础方面已经取得了迅速进展。通过研究这些发育系统在不同生物体之间保守或改变的程度,可以深入了解产生我们周围生物多样性的进化事件。黑腹果蝇早期模式形成的分子和遗传基础得到了特别深入的研究,与其他昆虫的比较揭示了发育某些方面的保守性,以及可能解释早期模式形成事件差异的不同之处。