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[来自热带地区的归国患者中的病毒疾病]

[Virus diseases in patients returning from the tropics].

作者信息

Hufert F T, Schmitz H

机构信息

Abteilung Virologie, Universität Freiburg.

出版信息

Ther Umsch. 1994 Aug;51(8):569-76.

PMID:7940415
Abstract

The high density of populations and insufficient sanitary conditions increases the risk to acquire viral diseases in tropical areas. This holds true for ubiquitous as well as for regional viral infections. Hepatitis and AIDS are found worldwide, but play a dominant role in tropical areas. Classical tropical viral infections are zoonoses. They are primarily infections of nonhuman vertebrates (e.g. rodents) and of arthropod vectors and can be transmitted to man. According to the clinical outcome these viral infections can be divided into three groups: influenza-like disease with arthralgia, encephalitis and hemorrhagic fevers. The majority of infections belong to the first group, followed by encephalitis cases. Viral hemorrhagic fevers are rare in visitors of tropical areas. Antibody detection is the method of choice in the diagnosis of tropical viral infections. In special situations (e.g. Lassa fever) the direct detection of the virus by PCR can be helpful. Tests for the detection of arboviruses, filoviruses and arenaviruses are only performed at a few centers worldwide.

摘要

热带地区人口密度高且卫生条件不足,增加了感染病毒性疾病的风险。无论是普遍存在的病毒感染还是区域性病毒感染都是如此。肝炎和艾滋病在全球范围内都有发现,但在热带地区更为突出。典型的热带病毒感染为人畜共患病。它们主要感染非人类脊椎动物(如啮齿动物)和节肢动物媒介,并可传播给人类。根据临床结果,这些病毒感染可分为三组:伴有关节痛的流感样疾病、脑炎和出血热。大多数感染属于第一组,其次是脑炎病例。病毒性出血热在热带地区的游客中很少见。抗体检测是诊断热带病毒感染的首选方法。在特殊情况下(如拉沙热),通过聚合酶链反应直接检测病毒可能会有所帮助。检测虫媒病毒、丝状病毒和沙粒病毒的试验仅在全球少数几个中心进行。

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