Berstad A, Berstad K, Hatlebakk J G, Wilhelmsen I, Nysaeter G, Bang C J, Hausken T, Nesje L B, Hjartholm A S, Hundal O
Gastroenterologisk seksjon, Haukeland Sykehus, Bergen.
Tidsskr Nor Laegeforen. 1994 Sep 10;114(21):2477-9.
We treated 143 Helicobacter pylori positive ulcer patients (duodenal ulcer 81, gastric ulcer 24, pyloric ulcer nine, previous duodenal ulcer 27, others two) with a ten days regimen of bismuth subnitrate, oxytetracycline and metronidazole. Four weeks after cessation of treatment the 14C-urea breath test showed that the infection was eradicated in 133 out of 140 patients (95%). The ulcer had healed in 129 (97%) of the H. pylori negative patients. Status at one year after treatment showed that 121 (98.4%) of 123 patients who had become H. pylori negative had remained negative. None of the H. pylori negative patients experienced ulcer relapse. The results show that the treatment is effective and that the rate of recurrence of H. pylori during the first year is very low.
我们采用次硝酸铋、土霉素和甲硝唑的十天疗程治疗了143例幽门螺杆菌阳性溃疡患者（十二指肠溃疡81例、胃溃疡24例、幽门溃疡9例、既往十二指肠溃疡27例、其他2例）。治疗结束四周后，14C-尿素呼气试验显示，140例患者中有133例（95%）感染被根除。幽门螺杆菌阴性的患者中有129例（97%）溃疡已愈合。治疗一年后的情况显示，123例转为幽门螺杆菌阴性的患者中有121例（98.4%）仍为阴性。幽门螺杆菌阴性的患者均未出现溃疡复发。结果表明该治疗有效，且第一年幽门螺杆菌的复发率非常低。
