Middleton D, Martin J, Douglas J, McClelland M
Northern Ireland Tissue Typing Laboratory and Renal Unit, City Hospital, Belfast.
Transplantation. 1994 Oct 15;58(7):845-8.
Patients awaiting a renal transplant were given 1 HLA-DR antigen-matched blood in order to compare the sensitization and graft outcome of these patients with those of control patients, who had been given random blood before transplantation. No differences in sensitization, measured by the formation of HLA antibodies, or in graft survival were found between the 2 groups. However, the incidence of rejection episodes was significantly reduced in the patients who received blood matched for 1 HLA-DR antigen compared with the patients who received random blood.
为了比较等待肾移植患者与对照组患者（移植前接受随机血型血液）的致敏情况和移植物结局，给等待肾移植的患者输注了1份HLA-DR抗原匹配的血液。两组在通过HLA抗体形成来衡量的致敏情况或移植物存活率方面未发现差异。然而，与接受随机血型血液的患者相比，接受1份HLA-DR抗原匹配血液的患者排斥反应发生率显著降低。
