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[无症状菌尿作为动态人类应激适应过程中内源性微生物群激活与持续存在综合征的表现]

[Asymptomatic bacteriuria as the manifestation of a syndrome of the activation and persistence of endogenous microflora in dynamic human adaptation to stress].

作者信息

Berdichevskiĭ B A, Tsvettsikh V E, Lerner G Ia, Krylov V I, Kashuba E A, Kazeko N I, Sultanbaev R A, Izgeĭm V P

出版信息

Urol Nefrol (Mosk). 1993 Mar-Apr(2):12-6.

PMID:7941134
Abstract

The analysis has been performed of the mechanisms underlying the origin of asymptomatic bacteriuria as an adaptive reaction in response to surgical aggression. The experiments proved penetration of autobacteria from the intestine to blood channel and organic structures of the animals in the course of adaptation to an operative trauma and consequent elimination of the bacteria from the body. It was observed that endogenic microflora participates in regeneration of macroorganism structures which have lost their morphofunctional integrity due to mechanic and toxic aggression. It is suggested that activation and persistence of endogenic microflora may arise to identify and abolish foci of aseptic destruction during the aggression in adaptation to stress.

摘要

已对无症状菌尿作为对手术侵袭的适应性反应的起源机制进行了分析。实验证明,在适应手术创伤及随后从体内清除细菌的过程中,自身细菌可从肠道渗透至动物的血道和器官结构。据观察,内源性微生物群参与了因机械性和毒性侵袭而失去形态功能完整性的宏观生物体结构的再生。有人提出,内源性微生物群的激活和持续存在可能是为了在适应应激的侵袭过程中识别并消除无菌性破坏灶。

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