Berdichevskiĭ B A, Tsvettsikh V E, Lerner G Ia, Krylov V I, Kashuba E A, Kazeko N I, Sultanbaev R A, Izgeĭm V P, Kiianiuk N S
Khirurgiia (Mosk). 1993 May(5):63-6.
The authors studied the mechanisms of bacterial dissemination in operative wounds in patients after various surgical interventions. It was demonstrated in experiments that during adaptation of the organism to the operative stress, autobacteria enter the blood from the intestinal reservoir and are eliminated through the urinary tract and wound surfaces, if foci of mechanical or toxic destruction exist the autobacteria precipitate in the affected tissues and participate directly in the reparative processes. On the basis of the obtained data it is suggested that the phenomenon of activation and persistence of endogenous microflora exists as one of the syndromes of adaptation of man to the aggression factor, which is aimed at revealing and removing the foci of tissue destruction developing as the result of exposure to the effect of the stress.
作者研究了各类外科手术后患者手术伤口中细菌传播的机制。实验表明,在机体适应手术应激过程中,自身细菌从肠道菌库进入血液,并通过尿道和伤口表面排出,若存在机械性或毒性破坏病灶,自身细菌会在受影响组织中沉淀并直接参与修复过程。基于所获数据,提示内源性微生物群激活和持续存在的现象作为人类适应攻击因子综合征之一存在,其目的是揭示和清除因应激作用而产生的组织破坏病灶。