Kurilo L F, Liubashevskaia I A, Dubinskaia V P, Gaeva T N
Urol Nefrol (Mosk). 1993 Mar-Apr(2):45-7.
A quantitative karyological analysis of immature male sex cell (IMSC) composition in ejaculate of males with normal spermogram (a relative standard), oligo-, astheno-, terato- or azoospermia has been made. The specimens were obtained from 100 patients. Because of IMSC absence, a part of the 150 specimens lacked informative value. The proportion of IMSC from ejaculate of fertile patients with normospermia was less than 4%. The cells were mainly spermatids, 26% of which remained unseparated in meiotic division. In oligozoospermia the number of ejaculate IMSC increased (up to 26.4%) as well as that of spermatocytes at the stage of meiotic pachytene and diplotene. The same trend persisted in asthenozoospermic males. In azoospermia the percent of IMSC averaged 52.4% varying greatly from individual to individual. Characteristic for this condition was also increased number of unseparated spermatids. The advantages and prospects of the method are discussed.
对精子图谱正常（相对标准）、少精子症、弱精子症、畸形精子症或无精子症男性射精液中未成熟男性生殖细胞（IMSC）组成进行了定量核型分析。样本取自100名患者。由于缺乏IMSC，150份样本中有一部分缺乏信息价值。正常精子生育力患者射精液中IMSC的比例低于4%。细胞主要是精子细胞，其中26%在减数分裂中未分离。少精子症患者射精液中IMSC数量增加（高达26.4%），减数分裂粗线期和双线期精母细胞数量也增加。弱精子症男性也存在同样的趋势。无精子症患者中IMSC的百分比平均为52.4%，个体差异很大。这种情况的特征还包括未分离精子细胞数量增加。讨论了该方法的优点和前景。
