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[髋关节病患者质子自旋断层扫描相关性的实验与临床研究]

[Experimental and clinical studies on the relevance of proton spin tomography in patients with coxarthrosis].

作者信息

Seubert P, Scherer M, Becker W, Fischer H J, Bückmann F W

机构信息

Institut für Kernspintomographie Herdecke.

出版信息

Z Orthop Ihre Grenzgeb. 1994 Jul-Aug;132(4):272-8. doi: 10.1055/s-2008-1039974.

DOI:10.1055/s-2008-1039974
PMID:7941685
Abstract

We examined 2 in formalin fixed hip specimens from a corpse, 27 patients with coxarthrosis and 3 healthy young volunteers with MRT concerning the illustration of the hip joint and pathological changes by coxarthrosis. Specimen of the femoral head after endoprosthetic operation could be achieved in 18 cases for comparison with MRT. All pathological alterations as cartilage alterations, sclerosis, cysts, effusion, edema, fibrosis were figured with high sensitivity. Cartilage was figured much better by gradient echo sequence with short echo time than by spin echo sequence. Gradient echo sequence made it possible to figure and quantify thinning of cartilage with high sensitivity. Both sequences showed artefacts because of the chemical shift in the area of the cartilage-bone boundary, which impaired especially the judgement of cartilage by spin echo sequence. Gradient echo sequence allowed because of the phase-contrast effect the distinction of hematopoietic and fatty bone marrow and possibly the delineation of bone marrow edema.

摘要

我们检查了取自一具尸体的2个经福尔马林固定的髋关节标本、27例髋关节病患者以及3名健康年轻志愿者的髋关节磁共振成像(MRT),以观察髋关节的影像及髋关节病的病理变化。18例患者获得了人工关节置换术后的股骨头标本用于与磁共振成像作对比。所有病理改变,如软骨改变、硬化、囊肿、积液、水肿、纤维化等均能以高灵敏度显示。与自旋回波序列相比,采用短回波时间的梯度回波序列能更好地显示软骨。梯度回波序列能够高灵敏度地显示并量化软骨变薄情况。由于软骨-骨边界区域的化学位移,两种序列均显示出伪影,这尤其影响了自旋回波序列对软骨的判断。由于相位对比效应,梯度回波序列能够区分造血骨髓和脂肪骨髓,并有可能勾勒出骨髓水肿情况。

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