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[乳胶凝集试验在儿童沙门氏菌病快速诊断中的应用]

[The use of the latex agglutination test for the rapid diagnosis of salmonellosis in children].

作者信息

Miliutina L N, Tendetnik Iu Ia

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1994 May-Jun(3):73-8.

PMID:7941873
Abstract

From 237 children hospitalized in the enteric department of an infectious clinic 381 fecal samples were obtained and examined (after 24-hour pre-cultivation in selenite enrichment medium) in the latex agglutination test. The results thus obtained were compared with the data of the bacteriological study of these samples. For the first time the diagnostic value of the latex agglutination test (LAT) both for the early and retrospective diagnosis of Salmonella mono- and combined infections was established. The possibility of using LAT for augmenting the laboratory determination of salmonellosis, on the average, 2.1-fold in cases of acute enteric infections, including 3.3-fold in mild and non-manifest forms of such infections and 6.2-fold in clinical variants of the disease with lesions of the proximal sections of the gastrointestinal tract, was demonstrated.

摘要

从一家传染病诊所肠道科收治的237名儿童中获取了381份粪便样本,并(在亚硒酸盐增菌培养基中进行24小时预培养后)进行乳胶凝集试验检测。将由此获得的结果与这些样本的细菌学研究数据进行比较。首次确定了乳胶凝集试验(LAT)对沙门氏菌单一感染和混合感染的早期及回顾性诊断的诊断价值。结果表明,在急性肠道感染病例中,使用LAT平均可使沙门氏菌病的实验室检测增加2.1倍,在轻度和无明显症状的此类感染中增加3.3倍,在伴有胃肠道近端病变的疾病临床变体中增加6.2倍。

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