Moffitt J E, Gearhart J G, Yates A B
University of Mississippi Medical Center, Jackson.
Am Fam Physician. 1994 Oct;50(5):1039-50, 1053-5.
Management of chronic asthma has changed significantly in recent years. Most of the changes in management are the result of an increased recognition of the importance of the inflammatory component in the pathogenesis and treatment of asthma. The National Heart, Lung, and Blood Institute issued guidelines for the management of asthma in 1991. Beta agonists, cromolyn and nedocromil are mainstays of treatment in patients with mild to moderate asthma. Inhaled steroids are useful in the treatment of patients with moderate to severe asthma. Nonpharmacologic management of asthma includes avoidance of allergens and irritants, the use of peak flow meters, and patient and family education.
近年来,慢性哮喘的管理发生了显著变化。管理方面的大多数变化是由于对哮喘发病机制和治疗中炎症成分重要性的认识不断提高。美国国立心肺血液研究所于1991年发布了哮喘管理指南。β受体激动剂、色甘酸钠和奈多罗米是轻至中度哮喘患者的主要治疗药物。吸入性糖皮质激素对中至重度哮喘患者的治疗有效。哮喘的非药物管理包括避免接触过敏原和刺激物、使用峰流速仪以及对患者及其家属进行教育。