Pendergrass S M
National Institute for Occupational Safety and Health, Robert A. Taft Laboratories, Cincinnati, Ohio 45226.
Am Ind Hyg Assoc J. 1994 Aug;55(8):733-7. doi: 10.1080/15428119491018628.
A comprehensive approach to estimating worker exposure to o-toluidine, aniline, and nitrobenzene using a combination of surface wipe, dermal badge, and air samples is described. Desorption of each sample was accomplished with ethanol followed by analyses using capillary gas chromatography with flame ionization detection. Analyte recovery was maximized when the gauze wipes and dermal badges were immediately desorbed in ethanol after sample collection. Sample collection of the airborne analytes was improved over previous solid sorbent samples by using a sampling train consisting of an acid-treated glass fiber filter in series with a large capacity silica gel tube (520/260 mg). The greatest recoveries of aniline and o-toluidine were from the acid-treated glass fiber filters and nitrobenzene from the large capacity silica gel sorbent tubes. The limit of detection for each analyte (1 micrograms) was approximately 10 times more sensitive than reported in previous National Institute for Occupational Safety and Health methods. Analyte recoveries for air samples were greatest under conditions of moderate relative humidity (53%), moderate sample volumes (< 50 L), and low flow rates (0.2 L/min). The overall relative standard deviation of the analytical method was 4.3%.
本文描述了一种综合方法，该方法结合表面擦拭、皮肤徽章和空气采样来估算工人对邻甲苯胺、苯胺和硝基苯的暴露情况。每个样品用乙醇解吸，然后使用带有火焰离子化检测的毛细管气相色谱法进行分析。当纱布擦拭物和皮肤徽章在样品采集后立即用乙醇解吸时，分析物回收率最高。通过使用由串联的酸处理玻璃纤维滤器和大容量硅胶管（520/260毫克）组成的采样系列，空气中分析物的样品采集比以前的固体吸附剂样品有所改进。苯胺和邻甲苯胺的最大回收率来自酸处理玻璃纤维滤器，硝基苯的最大回收率来自大容量硅胶吸附管。每种分析物的检测限（1微克）比以前美国国家职业安全与健康研究所方法报告的灵敏度高约10倍。在相对湿度适中（53%）、样品体积适中（<50升）和流速较低（0.2升/分钟）的条件下，空气样品的分析物回收率最高。该分析方法的总体相对标准偏差为4.3%。
