人类中性粒细胞中纤维状颗粒的超微结构
Ultrastructure of fibrillar granules in human neutrophils.
作者信息
Takemori N, Hirai K, Onodera R, Saito N, Miyokawa N
机构信息
Third Department of Internal Medicine, Asahikawa Medical College, Japan.
出版信息
Am J Hematol. 1994 Nov;47(3):232-4. doi: 10.1002/ajh.2830470316.
Fibrillar granules (FGs) represent neutrophilic primary granules containing clustered filaments. We investigated neutrophils in the bone marrow obtained from 17 patients with chronic myeloproliferative disorders (CMPD) by electron microscopy. FG-positive neutrophils were seen in 15 of the 17 CMPDs with varying frequencies. The diameter of FG-filaments was 7-8 nm, showing that they corresponded to neither intermediate filaments nor actin filaments.
纤维状颗粒（FGs）是含有成束细丝的嗜中性粒细胞初级颗粒。我们通过电子显微镜研究了17例慢性骨髓增殖性疾病（CMPD）患者骨髓中的嗜中性粒细胞。在17例CMPD患者中的15例中观察到了FG阳性嗜中性粒细胞，频率各不相同。FG细丝的直径为7-8纳米，表明它们既不对应于中间丝也不对应于肌动蛋白丝。
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