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采用腔内支架挽救血液透析移植物。

Hemodialysis graft salvage with endoluminal stents.

作者信息

Hood D B, Yellin A E, Richman M F, Weaver F A, Katz M D

机构信息

Department of Surgery, University of Southern California School of Medicine, LAC+USC Medical Center 90033.

出版信息

Am Surg. 1994 Oct;60(10):733-7.

PMID:7944033
Abstract

The most common cause of failure of hemodialysis access sites is stenosis within the site. The stenoses have traditionally been corrected surgically, but endovascular techniques may be an alternative method to treat these flow-limiting lesions and maintain graft patency. Over a recent 17-month period, endoluminal stents to relieve stenoses resistant to balloon dilatation alone were placed in 14 access sites. All sites were located on the upper extremity (13 PTFE bridge grafts and 1 A-V fistula). A total of 20 stents were placed: seven at the venous anastomosis, 12 in the venous outflow tract (including 3 in the subclavian vein), and one within the graft. Nine patients had placement of a single stent, four patients had two stents placed, and one patient had three. An additional eight stenotic lesions within these 14 sites were successfully dilated without need of a stent. After stent placement, these 14 sites have remained functional for a mean of 6.2 months. Four were functioning without further intervention at a mean of 8.5 months. Nine sites occluded at a mean of 4.7 months. The remaining site remained functional until death of the patient 10 months after stent placement. Of the nine failed sites, four developed restenosis at the site of stent placement, four developed stenoses at other sites, and the other site was abandoned. Three stents were placed in subclavian vein stenoses, and none of these has failed. Further study is necessary to determine whether endovascular stenting of dialysis access site stenoses will prove to be a durable, cost-effective alternative to surgical revision.

摘要

血液透析通路部位失败的最常见原因是该部位的狭窄。传统上,狭窄是通过手术矫正的,但血管腔内技术可能是治疗这些限制血流的病变并维持移植物通畅的一种替代方法。在最近17个月的时间里,在14个通路部位放置了腔内支架,以缓解仅靠球囊扩张难以解决的狭窄。所有部位均位于上肢(13个聚四氟乙烯桥接移植物和1个动静脉内瘘)。共放置了20个支架:7个位于静脉吻合口,12个位于静脉流出道(包括3个位于锁骨下静脉),1个位于移植物内。9例患者放置了单个支架,4例患者放置了2个支架,1例患者放置了3个支架。这14个部位内另外8个狭窄病变成功扩张,无需放置支架。放置支架后,这14个部位平均保持功能6.2个月。4个部位在平均8.5个月时无需进一步干预仍在正常工作。9个部位在平均4.7个月时闭塞。其余部位在放置支架10个月后患者死亡前一直保持功能。在9个失败的部位中,4个在支架放置部位出现再狭窄,4个在其他部位出现狭窄,另一个部位被废弃。3个支架放置在锁骨下静脉狭窄处,均未失败。有必要进一步研究以确定透析通路部位狭窄的血管腔内支架置入术是否将被证明是一种持久、经济有效的手术修复替代方法。

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