Both pro-uPA and uPA: PAI-1 complex bind to the alpha 2-macroglobulin receptor/LDL receptor-related protein. Evidence for multiple independent contacts between the ligands and receptor. - Suppr | 超能文献

Both pro-uPA and uPA: PAI-1 complex bind to the alpha 2-macroglobulin receptor/LDL receptor-related protein. Evidence for multiple independent contacts between the ligands and receptor.

作者信息

Nykjaer A, Kjøller L, Cohen R L, Lawrence D A, Gliemann J, Andreasen P A

机构信息

Department of Medical Biochemistry, University of Aarhus, Denmark.

出版信息

Ann N Y Acad Sci. 1994 Sep 10;737:483-5. doi: 10.1111/j.1749-6632.1994.tb44346.x.

DOI:10.1111/j.1749-6632.1994.tb44346.x

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Both pro-uPA and uPA: PAI-1 complex bind to the alpha 2-macroglobulin receptor/LDL receptor-related protein. Evidence for multiple independent contacts between the ligands and receptor.

Ann N Y Acad Sci. 1994 Sep 10;737:483-5. doi: 10.1111/j.1749-6632.1994.tb44346.x.

2

Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase against binding to the endocytic receptor.参与尿激酶-1型抑制剂复合物和尿激酶原与内吞性α2-巨球蛋白受体/低密度脂蛋白受体相关蛋白结合的区域。尿激酶受体保护尿激酶原不与内吞性受体结合的证据。

J Biol Chem. 1994 Oct 14;269(41):25668-76.

3

Binding of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex to the endocytosis receptors alpha2-macroglobulin receptor/low-density lipoprotein receptor-related protein and very-low-density lipoprotein receptor involves basic residues in the inhibitor.尿激酶型纤溶酶原激活物-纤溶酶原激活物抑制剂-1复合物与内吞作用受体α2-巨球蛋白受体/低密度脂蛋白受体相关蛋白及极低密度脂蛋白受体的结合涉及抑制剂中的碱性残基。

Biochem J. 1998 Jan 1;329 ( Pt 1)(Pt 1):55-63. doi: 10.1042/bj3290055.

4

Analysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related protein.低密度脂蛋白受体相关蛋白中尿激酶型纤溶酶原激活物-纤溶酶原激活物抑制剂-1复合物双结构域结合位点的分析

Biochem J. 2001 Jul 1;357(Pt 1):289-96. doi: 10.1042/0264-6021:3570289.

5

Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes.纯化的α2-巨球蛋白受体/低密度脂蛋白受体相关蛋白结合尿激酶-纤溶酶原激活物抑制剂1型复合物。α2-巨球蛋白受体介导尿激酶受体结合复合物细胞内降解的证据。

J Biol Chem. 1992 Jul 25;267(21):14543-6.

6

Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates cellular uptake of pro-urokinase.低密度脂蛋白受体相关蛋白/α2-巨球蛋白受体介导尿激酶原的细胞摄取。

J Biol Chem. 1993 Oct 15;268(29):21862-7.

7

Degradation of urokinase plasminogen activator (UPA) in endometrial stromal cells requires both the UPA receptor and the low-density lipoprotein receptor-related protein/alpha2-macroglobulin receptor.子宫内膜基质细胞中尿激酶型纤溶酶原激活剂（UPA）的降解既需要UPA受体，也需要低密度脂蛋白受体相关蛋白/α2-巨球蛋白受体。

Mol Hum Reprod. 1998 Jun;4(6):585-93. doi: 10.1093/molehr/4.6.585.

8

Binding areas of urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex for endocytosis receptors of the low-density lipoprotein receptor family, determined by site-directed mutagenesis.通过定点诱变确定尿激酶型纤溶酶原激活剂-纤溶酶原激活剂抑制剂-1复合物与低密度脂蛋白受体家族内吞作用受体的结合区域。

FEBS J. 2006 Nov;273(22):5143-59. doi: 10.1111/j.1742-4658.2006.05511.x. Epub 2006 Oct 17.

9

Analysis of ligand binding to the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that lipoprotein lipase and the carboxyl-terminal domain of the receptor-associated protein bind to the same site.配体与α2-巨球蛋白受体/低密度脂蛋白受体相关蛋白结合的分析。脂蛋白脂肪酶和受体相关蛋白的羧基末端结构域结合至同一位点的证据。

J Biol Chem. 1995 Oct 6;270(40):23713-9. doi: 10.1074/jbc.270.40.23713.

10

Specificity of serine proteinase/serpin complex binding to very-low-density lipoprotein receptor and alpha2-macroglobulin receptor/low-density-lipoprotein-receptor-related protein.丝氨酸蛋白酶/丝氨酸蛋白酶抑制剂复合物与极低密度脂蛋白受体及α2-巨球蛋白受体/低密度脂蛋白受体相关蛋白结合的特异性

Eur J Biochem. 1997 Sep 1;248(2):270-81. doi: 10.1111/j.1432-1033.1997.00270.x.

引用本文的文献

1

Serpin-Enzyme Receptors LDL Receptor-Related Protein 1.丝氨酸蛋白酶抑制剂-酶受体低密度脂蛋白受体相关蛋白1

Methods Enzymol. 2011;499:17-31. doi: 10.1016/B978-0-12-386471-0.00002-X.

2

Suppression of uPA and uPAR blocks radiation-induced MCP-1 mediated recruitment of endothelial cells in meningioma.抑制 uPA 和 uPAR 可阻断放射性诱导的脑膜瘤中单核细胞趋化蛋白-1 介导的内皮细胞募集。

Cell Signal. 2011 Aug;23(8):1299-310. doi: 10.1016/j.cellsig.2011.03.011. Epub 2011 Mar 21.