Lee W L
Department of Neurology, Tan Tock Seng Hospital, Singapore.
Ann Acad Med Singap. 1994 May;23(3):387-90.
The benign nature of febrile seizures (FS) has been well documented by large prospective population-based studies published between 1976 to 1987. However, many paediatricians still treat FS as though it is a serious condition which may cause brain damage, and epileptologists and neurosurgeons continue to debate the role of FS in causing temporal lobe epilepsy. The efficacy of long-term anticonvulsant therapy has recently been questioned and the possibility of permanent cognitive impairment after long-term phenobarbital has caused public alarm. This article attempts to review the areas of controversy and suggest a rational approach to the investigation and management of FS.
1976年至1987年间发表的大型前瞻性人群研究充分证明了热性惊厥(FS)的良性本质。然而,许多儿科医生仍将FS视为可能导致脑损伤的严重病症,癫痫学家和神经外科医生也在继续争论FS在导致颞叶癫痫中的作用。长期抗惊厥治疗的疗效最近受到质疑,长期使用苯巴比妥后出现永久性认知障碍的可能性引起了公众的恐慌。本文试图回顾争议领域,并提出对FS进行调查和管理的合理方法。