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[肝功能对肝细胞癌立体定向微波组织凝固治疗的影响]

[Influence of liver function on stereotactic microwave tissue coagulation therapy for hepatocellular carcinoma].

作者信息

Hiraki M, Kurohiji T, Kimitsuki H, Kakegawa T, Watanabe J, Yamashita Y

机构信息

1st Dept. of Surgery, Kurume University School of Medicine.

出版信息

Gan To Kagaku Ryoho. 1994 Sep;21(13):2215-7.

PMID:7944443
Abstract

We studied 21 cases of hepatocellular carcinoma with liver cirrhosis to investigate the influence of liver function on stereotactic microwave tissue coagulation therapy. The cases were divided into three groups by the operation. The first group received only hepatectomy, the second hepatectomy and coagulation therapy for any remaining tumor, and the third group received only coagulation therapy. In group one, the average value of ICG R15 increased from 26.6% to 33.8%. In group 2, the average value of ICG R15 increased from 18.9% to 32.1%. And in group 3, the initial ICG R15 was 26.1%; after four weeks, the ICG test was 25.4%. These results showed that coagulation therapy alone had less influence on hepatic function. We propose that the coagulation therapy should be selected for cases of HCC with liver cirrhosis which have a poor liver function.

摘要

我们研究了21例伴有肝硬化的肝细胞癌患者,以探讨肝功能对立体定向微波组织凝固治疗的影响。根据手术方式将病例分为三组。第一组仅接受肝切除术,第二组接受肝切除术并对任何残留肿瘤进行凝固治疗,第三组仅接受凝固治疗。在第一组中,吲哚菁绿滞留率(ICG R15)的平均值从26.6%升至33.8%。在第二组中,ICG R15的平均值从18.9%升至32.1%。而在第三组中,初始ICG R15为26.1%;四周后,吲哚菁绿试验结果为25.4%。这些结果表明,单纯凝固治疗对肝功能的影响较小。我们建议,对于肝功能较差的伴有肝硬化的肝癌病例,应选择凝固治疗。

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