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肝硬化患者肝切除手术风险的术前评估

Preoperative estimation of surgical risk of hepatectomy in cirrhotic patients.

作者信息

Noguchi T, Imai T, Mizumoto R

机构信息

1st Department of Surgery, Mie University School of Medicine, Tsu-City, Japan.

出版信息

Hepatogastroenterology. 1990 Apr;37(2):165-71.

PMID:2160419
Abstract

In order to improve the results of hepatectomy in cirrhotic patients, functional resectability of the liver was evaluated before surgery, in 119 cases of hepatectomy, including 85 cases with cirrhosis, over the last 10 years. Our total risk, measured by multivariate analysis of hepatic function tests, was very useful in selecting the suitable operative method. Functional reserve of the remnant liver and that of per unit volume of the liver evaluated by ICGRmax, were also good indicators for estimating long-term prognosis and liver regeneration following hepatectomy. Furthermore, from our experience with 4 cirrhotic patients who developed disseminated intravascular coagulopathy after hepatectomy, the preoperative evaluation of function in the coagulation-fibrinolysis system was also important for estimating the operative risk of hepatectomy in cirrhotic patients.

摘要

为提高肝硬化患者肝切除术的效果,在过去10年里,我们对119例肝切除术患者(其中85例为肝硬化患者)术前评估了肝脏的功能可切除性。通过对肝功能检查进行多因素分析得出的总体风险,在选择合适的手术方法时非常有用。通过吲哚氰绿最大清除率(ICGRmax)评估的残余肝脏功能储备以及肝脏单位体积的功能储备,也是估计肝切除术后长期预后和肝脏再生的良好指标。此外,根据我们对4例肝切除术后发生弥散性血管内凝血的肝硬化患者的经验,术前评估凝血-纤溶系统的功能对于估计肝硬化患者肝切除术的手术风险也很重要。

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