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针对伴有侧支供血的肝细胞癌的“包裹疗法”

["Wrapping therapy" for hepatocellular carcinomas with collateral feeders].

作者信息

Sasaki Y, Imaoka S, Nakano H, Yasuda T, Nakamori S, Kameyama M, Ohigashi H, Hiratsuka M, Kabuto T, Ishikawa O

机构信息

Dept. of Surgery, Center for Adult Diseases, Osaka.

出版信息

Gan To Kagaku Ryoho. 1994 Sep;21(13):2237-40.

PMID:7944449
Abstract

A new treatment method to intercept collaterals with silicone rubber sheeting, called "wrapping therapy", was used for 18 patients with advanced hepatocellular carcinomas having collateral feeders from other organs surrounding the liver. Chemoembolization in 17 of the 18 patients in whom it had been conducted more than once, had proven ineffective. Obvious collateral feeders (parasitic branches) to the tumors were recognized on hepatic angiograms in two-thirds of the patients. This procedure was followed by regional chemotherapy and/or chemoembolization. The 3- and 4-year survival rates of the patients after "wrapping therapy" were 54% and 54%, respectively. This therapy is worth using for hepatocellular carcinomas uncontrolled by arterial therapy because of development of collateral feeders.

摘要

一种用硅橡胶片阻断侧支循环的新治疗方法,称为“包裹疗法”,用于治疗18例晚期肝细胞癌患者,这些患者的肝脏周围有来自其他器官的侧支供血。18例患者中有17例曾多次进行化疗栓塞,均证明无效。三分之二的患者在肝血管造影中可识别出明显的肿瘤侧支供血(寄生分支)。该操作之后进行了区域化疗和/或化疗栓塞。“包裹疗法”后患者的3年和4年生存率分别为54%和54%。对于因侧支供血发展而无法通过动脉治疗控制的肝细胞癌,这种疗法值得应用。

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