Teramoto T, Onda M, Tokunaga A, Fujita I, Oguri T, Okuda T, Mizutani T, Kiyama T, Yoshiyuki T, Nishi K
First Dept. of Surgery, Nippon Medical School.
Gan To Kagaku Ryoho. 1994 Sep;21(13):2260-2.
We investigated the utility of intraoperative peritoneal lavage smears and gastric wall brushing smears for diagnosis of peritoneal dissemination and serosal involvement during gastric cancer surgery. One hundred fifty-three patients with gastric cancer were examined; 138 who underwent gastric resection and 15 who did not. The incidence of cancer cell positivity determined by these methods was 8.0% in resected cases, and 80.0% in unresected cases. According to macroscopic serosal invasion, the incidence of positive cytology was 0% for S0, 15.4% for S1, 13.0% for S2, and 38.7% for S3. According to microscopic wall invasion, the incidence of positivity was 0% for m and sm, 6.3% for mp, 0% for ss, and 22.2% for se and si. In terms of macroscopic peritoneal dissemination, the incidence of positivity was 2.6% for P0, 28.6% for P1, 42.9% for P2, and 90.0% for P3. These results suggest that peritoneal lavage smears and gastric wall brushing smears are useful for predicting the spread of peritoneal dissemination. Thus, further study of intraoperative fast-smear cytology seems warranted.
我们研究了术中腹腔灌洗涂片和胃壁刷片在胃癌手术中诊断腹膜播散和浆膜受累的实用性。对153例胃癌患者进行了检查;其中138例行胃切除术,15例未行胃切除术。通过这些方法确定的癌细胞阳性率在切除病例中为8.0%,在未切除病例中为80.0%。根据宏观浆膜侵犯情况,S0期细胞学阳性率为0%,S1期为15.4%,S2期为13.0%,S3期为38.7%。根据微观壁层侵犯情况,m和sm期阳性率为0%,mp期为6.3%,ss期为0%,se和si期为22.2%。就宏观腹膜播散而言,P0期阳性率为2.6%,P1期为28.6%,P2期为42.9%,P3期为90.0%。这些结果表明,腹腔灌洗涂片和胃壁刷片有助于预测腹膜播散的范围。因此,似乎有必要对术中快速涂片细胞学进行进一步研究。