[克氏综合征伴低促性腺激素性性腺功能减退及睾丸间质细胞缺失]

[Klinefelter syndrome with hypogonadotropic hypogonadism and absence of Leydig cells].

作者信息

Rodríguez de Ledesma J M, Cozar Olmo J M, Nistal Martín N, Cisneros J, Cuervo E, Martínez-Piñeiro J A

机构信息

Servicio de Urología, Hospital La Paz, Facultad de Medicina, Universidad Autónoma, Madrid, España.

出版信息

Arch Esp Urol. 1994 Jul-Aug;47(6):618-20.

PMID:7944607

Abstract

Klinefelter's syndrome is characterized by hypergonadotropic hypogonadism, 47,XXY karyotype, gynecomastia, azoospermia and testicular atrophy with hyalinization of seminiferous tubules and hyperplasia of Leydig cells. Some cases of Klinefelter's syndrome with unexplainably low levels of gonadotropins have been reported in the literature. Two additional cases of Klinefelter's syndrome with hypogonadotropic hypogonadism and absence of Leydig cells are described.

摘要

克兰费尔特综合征的特征为高促性腺激素性性腺功能减退、47,XXY核型、男子女性型乳房、无精子症以及睾丸萎缩伴生精小管玻璃样变和莱迪希细胞增生。文献中已报道了一些克兰费尔特综合征病例，其促性腺激素水平低得无法解释。本文描述了另外两例克兰费尔特综合征病例，其表现为低促性腺激素性性腺功能减退且无莱迪希细胞。