Zolotarevskiĭ V B, Sekamova S M, Chilingaridi K E
Arkh Patol. 1993 May-Jun;55(3):70-2.
The paper reports a case of thyroid cancer in a female patient aged 56 operated on for nodular euthyroid goiter. The tumor had a mixed histological structure of medullary-follicular cancer and resembled malignant hemangioendothelioma. Electron microscopy detected tumor cells of A- and C-cell type as well as nondifferentiated elements. The tumor contained deposits of amorphous mass deprived of tinctorial properties characteristic of APUD-amyloid and having fine-fibrillar material produced by tumor C-cells.
该论文报道了一例56岁女性甲状腺癌患者,该患者因结节性甲状腺肿接受手术治疗。肿瘤具有髓样-滤泡癌的混合组织学结构,类似恶性血管内皮瘤。电子显微镜检测到A细胞和C细胞类型的肿瘤细胞以及未分化成分。肿瘤中含有无定形物质沉积物,缺乏APUD淀粉样蛋白的染色特性,且含有肿瘤C细胞产生的细纤维物质。