Glasson W J, Hirst L W, Axelsen R A, Moon M
Department of Surgery, Princess Alexandra Hospital, Brisbane, Queensland.
Arch Ophthalmol. 1994 Oct;112(10):1342-5. doi: 10.1001/archopht.1994.01090220092029.
A 73-year-old man had been treated for a sore, red, left eye for 4 months before a clinical diagnosis of squamous cell carcinoma of the limbus was made. This diagnosis was confirmed on examination of a biopsy specimen, but after an initial surgical attempt to fully excise the tumor, there was clinical evidence of intraocular spread. An extensive corneoscleral resection and iridocyclectomy appeared to completely excise the tumor, as indicated by frozen section review. However, 1 year later, the patient re-presented with obvious residual squamous cell carcinoma of the iris and trabecular meshwork, well away from the original tumor site. Subsequent exenteration has resulted in a tumor-free patient for 1 year. Apparent surgical clearance of an extensive squamous cell carcinoma does not ensure total intraocular clearance of residual tumor, which may be remote from the original tumor site.
一名73岁男性因左眼疼痛、发红接受了4个月的治疗，之后才临床诊断为角膜缘鳞状细胞癌。活检标本检查证实了这一诊断，但在首次手术试图完全切除肿瘤后，有眼内扩散的临床证据。如冰冻切片检查所示，广泛的角膜巩膜切除术和虹膜睫状体切除术似乎完全切除了肿瘤。然而，1年后，患者再次出现明显的虹膜和小梁网残余鳞状细胞癌，远离原发肿瘤部位。随后的眼球摘除术使患者无瘤生存1年。广泛鳞状细胞癌的明显手术清除并不能确保残余肿瘤在眼内完全清除，残余肿瘤可能远离原发肿瘤部位。
