Zhang Zhe, Li Bin, Shi Jitong, Xu Xiaolin, Li Liaoqing, Gao Fei
Beijing Institute of Ophthalmology, Beijing TongRen Eye Center, Capital University of Medical Science, Beijing, China.
Ophthalmologica. 2007;221(3):200-3. doi: 10.1159/000099302.
Conjunctival squamous carcinoma, which is regarded as a low-grade malignancy, usually originates at the limbus. Most cases remain superficial to the sclera. Intraocular invasion is rarely reported. We describe a woman misdiagnosed as conjunctivitis and pterygium before a clinical diagnosis of conjunctival squamous cell carcinoma. The diagnosis was made by histopathological examination of the biopsy specimen. Examination revealed an elevated mass on the nasal limbus extending intraocularly. White flaky mass occupied approximately 3/7 space of the anterior chamber. Exenteration was performed for control of local lesion. Histopathologic analysis confirmed that intraocular involvement occurs through the emissary vessels near the area of limbus. The case highlights the need for accurate diagnosis and prompt intervention. A brief review of the clinical and histopathologic features of conjunctival squamous cell carcinoma is also presented.
结膜鳞状细胞癌被视为一种低级别恶性肿瘤，通常起源于角膜缘。大多数病例局限于巩膜表面。眼内侵犯鲜有报道。我们描述了一名女性，在临床诊断为结膜鳞状细胞癌之前，曾被误诊为结膜炎和翼状胬肉。诊断通过活检标本的组织病理学检查得以确定。检查发现鼻侧角膜缘有一隆起肿物，已向眼内扩展。白色片状肿物占据了前房约3/7的空间。为控制局部病变进行了眼球摘除术。组织病理学分析证实，眼内受累是通过角膜缘附近的导血管发生的。该病例强调了准确诊断和及时干预的必要性。同时还简要回顾了结膜鳞状细胞癌的临床和组织病理学特征。
