从牛血红蛋白消化水解物中分离得到的血啡肽对血管紧张素转换酶活性的抑制作用及抑制动力学
Inhibition and inhibition kinetics of angiotensin converting enzyme activity by hemorphins, isolated from a peptic bovine hemoglobin hydrolysate.
作者信息
Zhao Q, Sannier F, Garreau I, Guillochon D, Piot J M
机构信息
Laboratoire de Génie Protéique, Université de La Rochelle, France.
出版信息
Biochem Biophys Res Commun. 1994 Oct 14;204(1):216-23. doi: 10.1006/bbrc.1994.2447.
PMID:7945362
Abstract
The inhibitory effect on angiotensin converting enzyme (ACE) activity by hemorphins isolated from an enzymatic bovine hemoglobin hydrolysate was reported. Inhibitory kinetics proved that inhibition mechanism was non-competitive. The stability of hemorphins towards ACE was studied.
摘要
据报道，从酶解牛血红蛋白水解物中分离出的血啡肽对血管紧张素转换酶（ACE）活性具有抑制作用。抑制动力学证明其抑制机制为非竞争性。研究了血啡肽对ACE的稳定性。
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