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[薄雪火绒草对动物反向被动阿尔图斯(RPA)诱导的炎症的影响]

[Effect of Leontopodium leontopodioides (Willd.) Beauv. on inflammation induced by animal reversed passive arthus (RPA)].

作者信息

Li L Y, Ye J M, Yin H, Zhu Y M, Tian J M, Gao F

机构信息

Jilin Provincial Academy of Traditional Chinese Medicine and Materia Medica, Changchun.

出版信息

Zhongguo Zhong Yao Za Zhi. 1994 Mar;19(3):174-6, 192.

PMID:7945846
Abstract

The extract from Leontopodium leontopodioides 50-100mg/kg ip has been proved able to suppress the swelling of normal or adrenalectomised rat hind paws induced by RPA, and strongly inhibit the cutaneous hemorrhage of animals induced by RPA, lysosome or lysosome of broken membrane. It has also been shown that the extract 100 mg/kg ip can markedly inhibit the migration of leukocytes. These suggest that the anti-inflammatory properties of the extract are not dependent on the pituitary-adrenal system or membrane of lysosome.

摘要

阿尔泰银莲花提取物腹腔注射50-100mg/kg已被证明能够抑制由右旋糖酐硫酸酯钠(RPA)诱导的正常或肾上腺切除大鼠后爪肿胀,并强烈抑制由RPA、溶酶体或破裂膜的溶酶体诱导的动物皮肤出血。还表明,腹腔注射100mg/kg的提取物可显著抑制白细胞的迁移。这些表明提取物的抗炎特性不依赖于垂体-肾上腺系统或溶酶体膜。

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