两例胺碘酮所致甲状腺毒症患者在继续服用胺碘酮的同时，短期使用抗甲状腺药物治疗成功。
Two cases of amiodarone-induced thyrotoxicosis successfully treated with a short course of antithyroid drugs while amiodarone was continued.
作者信息
Trip M D, Düren D R, Wiersinga W M
机构信息
Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
出版信息
Br Heart J. 1994 Sep;72(3):266-8. doi: 10.1136/hrt.72.3.266.
Abstract
Two patients with amiodarone-induced thyrotoxicosis were treated successfully with potassium perchlorate and carbimazole while treatment with amiodarone was continued. These antithyroid drugs were stopped after the patients had became clinically and biochemically euthyroid. During follow up, when treatment with amiodarone continued, thyrotoxicosis did not recur. Amiodarone-induced thyrotoxicosis seems to be a transient condition that can be treated successfully with a short course of antithyroid drugs without stopping amiodarone treatment.
摘要
两名胺碘酮所致甲状腺毒症患者在继续使用胺碘酮治疗的同时，成功接受了高氯酸钾和卡比马唑治疗。在患者临床和生化指标恢复正常甲状腺功能后，停用了这些抗甲状腺药物。在随访期间，当继续使用胺碘酮治疗时，甲状腺毒症未复发。胺碘酮所致甲状腺毒症似乎是一种短暂性疾病，可通过短期使用抗甲状腺药物成功治疗，而无需停用胺碘酮治疗。
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本文引用的文献
1
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Am J Surg Pathol. 1987 Mar;11(3):197-204. doi: 10.1097/00000478-198703000-00004.
2
Is humoral thyroid autoimmunity relevant in amiodarone iodine-induced thyrotoxicosis (AIIT)?体液性甲状腺自身免疫在胺碘酮碘诱导的甲状腺毒症（AIIT）中是否相关？
Clin Endocrinol (Oxf). 1986 Jun;24(6):627-33. doi: 10.1111/j.1365-2265.1986.tb01658.x.
3
Amiodarone-associated thyrotoxicosis (AAT): experience with surgical management.
Surgery. 1987 Dec;102(6):1062-7.
4
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