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感染艾滋病毒女性的宫颈肿瘤形成

Cervical neoplasia in women with HIV infection.

作者信息

Maiman M

机构信息

Department of Obstetrics and Gynecology, State University of New York Health Science Center at Brooklyn.

出版信息

Oncology (Williston Park). 1994 Aug;8(8):83-9; discussion 89, 93-4.

PMID:7947005
Abstract

HIV infections in women now account for 40% of all HIV infections worldwide, and the majority of new infections are due to heterosexual transmission. In the United States, 12% of AIDS cases occur in women and in certain high prevalence areas such as Brooklyn, New York, 25% of cases are in women. Both squamous cell neoplasia of the cervix and HIV infection are, in part, sexually transmitted diseases, with oncogenic types of human papillomavirus infection the implicated viral carcinogen associated with cervical cancer. Therefore, an association between cervical cancer and AIDS can be anticipated on the basis of common sexual behavioral risk factors. The author summarizes what we know about the diagnosis and management of women with these problems.

摘要

目前,全球女性艾滋病毒感染病例占所有艾滋病毒感染病例的40%,且大多数新感染病例是由异性传播所致。在美国,12%的艾滋病病例发生在女性群体中,在某些高流行地区,如纽约布鲁克林,25%的病例为女性。宫颈癌的鳞状上皮瘤变和艾滋病毒感染在一定程度上均属于性传播疾病,致癌型人乳头瘤病毒感染被认为是与宫颈癌相关的病毒致癌物。因此,基于共同的性行为风险因素,可以预计宫颈癌与艾滋病之间存在关联。作者总结了我们对患有这些问题的女性的诊断和管理的了解。

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1
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引用本文的文献

1
Human Papillomavirus Infections in Cervical Samples From HIV-Positive Women: Evaluation of the Presence of the Nonavalent HPV Genotypes and Genetic Diversity.HIV阳性女性宫颈样本中的人乳头瘤病毒感染:九价人乳头瘤病毒基因型存在情况及基因多样性评估
Front Microbiol. 2020 Nov 25;11:603657. doi: 10.3389/fmicb.2020.603657. eCollection 2020.
2
Perspectives in HPV Secondary Screening and Personalized Therapy Basing on Our Understanding of HPV-Related Carcinogenesis Pathways.基于我们对 HPV 相关致癌途径的理解,探讨 HPV 二级筛查和个体化治疗的观点。
Mediators Inflamm. 2020 Mar 25;2020:2607594. doi: 10.1155/2020/2607594. eCollection 2020.
3
Review of HIV-Related Cytopathology.
人类免疫缺陷病毒相关细胞病理学综述
Patholog Res Int. 2011 Apr 7;2011:256083. doi: 10.4061/2011/256083.
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HPV as a model for the development of prophylactic and therapeutic cancer vaccines.人乳头瘤病毒作为预防性和治疗性癌症疫苗开发的模型。
Curr Mol Med. 2009 Aug;9(6):766-73. doi: 10.2174/156652409788970625.