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儿童肾活检:两种技术的比较

Renal biopsy in children: comparison of two techniques.

作者信息

Webb N J, Pereira J K, Chait P G, Geary D F

机构信息

Department of Paediatrics, Hospital for Sick Children, Toronto, Canada.

出版信息

Pediatr Nephrol. 1994 Aug;8(4):486-8. doi: 10.1007/BF00856542.

Abstract

Two hundred and thirty-five children who underwent percutaneous renal biopsy under real-time ultrasound guidance at The Hospital for Sick Children, between 1 January 1991 and 31 March 1993, were studied to compare the incidence of complications after biopsies with the Trucut needle (TN) and the Bard Biopty gun (BG). Of the 190 cases for which full clinical details were available and in which a single instrument was used for renal biopsy, 157 were biopsied with the BG and 33 with the TN. There was no significant difference between the two groups in variables such as age, weight, sex, number of needle passes and number of tissue cores obtained. The proportion of native and allograft biopsies in each group was similar. More children in the TN group underwent biopsy under general anaesthesia. Adequate diagnostic tissue samples were obtained in 189 of 190 cases. There were more complications in the TN group than in the BG group (P < 0.001). When allograft and native kidney biopsies were analysed separately, this difference in complications remained highly significant for the native kidney group (P < 0.005), though not for the allograft group. When the effect of needle size alone was investigated, there was no significant difference in the incidence of complications when TN biopsies were compared with 14-gauge BG biopsies or when 14- and 18-gauge BG biopsies were compared with each other.

摘要

1991年1月1日至1993年3月31日期间,在病童医院接受实时超声引导下经皮肾活检的235名儿童被纳入研究,以比较使用Trucut针(TN)和巴德活检枪(BG)进行活检后并发症的发生率。在190例可获取完整临床细节且使用单一器械进行肾活检的病例中,157例使用BG进行活检,33例使用TN进行活检。两组在年龄、体重、性别、穿刺针数和获取的组织芯数量等变量方面无显著差异。每组中自体肾活检和同种异体肾活检的比例相似。TN组中更多儿童在全身麻醉下进行活检。190例病例中有189例获得了足够的诊断性组织样本。TN组的并发症比BG组更多(P < 0.001)。当分别分析同种异体肾活检和自体肾活检时,自体肾组并发症的这种差异仍然非常显著(P < 0.005),而异种异体肾组则不然。当仅研究针的尺寸的影响时,将TN活检与14号BG活检进行比较,或将14号和18号BG活检相互比较时,并发症的发生率没有显著差异。

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