白化小鼠和有色小鼠视觉敏感度的电生理评估

Electrophysiological estimates of visual sensitivity in albino and pigmented mice.

作者信息

Green D G, Herreros de Tejada P, Glover M J

机构信息

Department of Ophthalmology, University of Michigan, Ann Arbor.

出版信息

Vis Neurosci. 1994 Sep-Oct;11(5):919-25. doi: 10.1017/s0952523800003874.

DOI:10.1017/s0952523800003874

PMID:7947405

Abstract

We have estimated the absolute threshold of congenic albino and pigmented mice (C57) using ERG, pupillary light reflex, and VEP. We are unable to detect strain differences using ERGs or VEPs, but pupillary thresholds appear to be different. In addition, as we have previously reported for rats, VEP thresholds are considerably lower than the ERG b-wave thresholds. The VEP thresholds agree with behavioral data from pigmented mice made by others. The mouse VEP thresholds are close to the VEP thresholds in rats and the psychophysical thresholds of two human observers.

摘要

我们使用视网膜电图（ERG）、瞳孔对光反射和视觉诱发电位（VEP）估计了同基因白化小鼠和有色小鼠（C57）的绝对阈值。我们无法通过ERG或VEP检测到品系差异，但瞳孔阈值似乎有所不同。此外，正如我们之前对大鼠的报道，VEP阈值远低于ERG b波阈值。VEP阈值与其他人对有色小鼠的行为数据一致。小鼠的VEP阈值接近大鼠的VEP阈值以及两名人类观察者的心理物理学阈值。