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肺炎克雷伯菌KAY2026利用L-山梨糖的sor操纵子序列。

Sequence of the sor-operon for L-sorbose utilization from Klebsiella pneumoniae KAY2026.

作者信息

Wehmeier U F, Lengeler J W

机构信息

Bergische Universität GH Wuppertal, Chemische Mikrobiologie, Germany.

出版信息

Biochim Biophys Acta. 1994 Oct 19;1208(2):348-51. doi: 10.1016/0167-4838(94)90124-4.

DOI:10.1016/0167-4838(94)90124-4
PMID:7947968
Abstract

We have sequenced the complete sor-operon of Klebsiella pneumoniae KAY2026. The operon has been mapped at 91 min on the Klebsiella gene-map. It comprises seven open reading frames for the genes sorCDFBAME, which are expressed from the single promotor sorCP. The gene sorC codes for a regulator protein that positively and negatively regulates the expression of the operon; sorD encodes a D-glucitol-6-phosphate dehydrogenase, the genes sorFBAM encode four proteins of a phosphoenolpyruvate-dependent L-sorbose-phosphotransferase system and sorE, finally, an L-sorbose-1-phosphate-reductase.

摘要

我们已对肺炎克雷伯菌KAY2026的完整sor操纵子进行了测序。该操纵子已定位在克雷伯菌基因图谱的91分钟处。它包含用于sorCDFBAME基因的七个开放阅读框,这些基因由单一启动子sorCP表达。基因sorC编码一种调节蛋白,该蛋白对操纵子的表达进行正向和负向调节;sorD编码一种D-葡萄糖醇-6-磷酸脱氢酶,基因sorFBAM编码磷酸烯醇丙酮酸依赖性L-山梨糖磷酸转移酶系统的四种蛋白质,最后,sorE编码一种L-山梨糖-1-磷酸还原酶。

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