Miethke C, Affeld K
Abt. Innere Medizin, Labor für Biofluidmechanik, Freie Universität Berlin.
Biomed Tech (Berl). 1994 Jul-Aug;39(7-8):181-7. doi: 10.1515/bmte.1994.39.7-8.181.
Presently available hydrocephalus valves still are not perfect. There are two major drawbacks: They have a tendency to clog and do not take into account the posture of the patient. The latter results in an intracranial pressure which is either too high or too low. To avoid these problems a new valve was designed which is described in this article. It introduces a pressure control: The force on the actual valve seat is augmented and balanced by a powerful spring. The large forces generated this way are able to overcome sticking forces due to fibrin or cellular debris. The valve functions well even with viscous and sticky cerebrospinal fluid (CSF). This mechanism maintains the pressure almost independent of the composition of the CSF. A valve insensitive to the posture of the patient can create an overdrainage, causing related problems such as subdural hygromas, slit ventricle syndrome, and consecutive proximal catheter obstruction. This is avoided by the valve presented here. It has two different pressure controllers: one designed for the supine position and another designed for the upright position of the patient. When the patient stands up or sits up, the pressure controller for the horizontal position is shut off by a gravity-activated sphere, and the drainage of CSF is directed into the appropriate controller for the upright position. In this way, the change of the hydrostatic differential pressure between the ventricles and the peritoneal cavity is taken into account and the intracranial pressure remains within physiological values. Laboratory investigations have shown that the new valve performs as designed.
目前可用的脑积水阀门仍不完美。存在两个主要缺点:它们容易堵塞,并且没有考虑患者的体位。后者会导致颅内压过高或过低。为避免这些问题,设计了一种新阀门,本文将对其进行描述。它引入了压力控制:实际阀座上的力通过一个强力弹簧得到增强和平衡。通过这种方式产生的大力能够克服由于纤维蛋白或细胞碎片引起的粘连力。即使对于粘性脑脊液(CSF),该阀门也能正常工作。这种机制维持压力几乎与脑脊液的成分无关。对患者体位不敏感的阀门可能会导致引流过度,引发诸如硬膜下积液、裂隙脑室综合征以及随后的近端导管阻塞等相关问题。本文介绍的阀门可避免这种情况。它有两种不同的压力控制器:一种是为患者仰卧位设计的,另一种是为患者直立位设计的。当患者站立或坐起时,用于水平位置的压力控制器会被一个重力激活球关闭,脑脊液的引流会导向适合直立位的控制器。通过这种方式,考虑到了脑室与腹腔之间静水压差的变化,颅内压保持在生理值范围内。实验室研究表明,这种新阀门按设计运行。