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[用于特发性正常压力脑积水的重力阀。60例患者的前瞻性研究]

[Gravity valves for idiopathic normal pressure hydrocephalus. A Prospective study of 60 patients].

作者信息

Meier U

机构信息

Klinik für Neurochirurgie, Unfallkrankenhaus Berlin.

出版信息

Nervenarzt. 2004 Jun;75(6):577-83. doi: 10.1007/s00115-004-1695-6.

Abstract

OBJECTIVE

Are hydrostatic valves superior to conventional differential pressure shunts in patients with normal- pressure hydrocephalus, with regard to the postoperative results of treatment and possible complications?

METHODS

From September 1997 to January 2002, 60 patients with idiopathic normal-pressure hydrocephalus were treated by surgical implantation of a hydrostatic valve (Miethke dual-switch valve) at the Unfallkrankenhaus Berlin.

RESULTS

One year after the shunt operation, the clinical picture was very good for 33% of the patients, good for 33%, satisfactory for 17%, and poor for 17%. At 20%, the rate of postoperative complications (catheter dislocations, valve infections, underdrainage and overdrainage) is still relatively high. The opening pressure of the Miethke dual-switch valve did not correlate with the postoperative results of treatment.

CONCLUSION

According to our experience, hydrostatic Miethke dual-switch valves are superior to conventional differential pressure shunts without an additional gravity unit, especially with regard to the treatment of patients with idiopathic normal -pressure hydrocephalus, concerning both the postoperative results of the treatment and the incidence of possible complications. With differentiated diagnosis and therapy, a clinical improvement can be achieved for 83% of such patients.

摘要

目的

就治疗的术后结果及可能的并发症而言,在正常压力脑积水患者中,流体静压阀是否优于传统的压差分流器?

方法

1997年9月至2002年1月,柏林创伤医院对60例特发性正常压力脑积水患者进行了流体静压阀(米特克双开关阀)的手术植入治疗。

结果

分流手术后一年,33%的患者临床状况非常好,33%良好,17%满意,17%差。术后并发症(导管移位、阀门感染、引流不足和引流过度)发生率仍相对较高,为20%。米特克双开关阀的开启压力与术后治疗结果无关。

结论

根据我们的经验,流体静压米特克双开关阀优于无附加重力装置的传统压差分流器,特别是在治疗特发性正常压力脑积水患者方面,无论是治疗的术后结果还是可能并发症的发生率。通过鉴别诊断和治疗,83%的此类患者可实现临床改善。

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