• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名患有SHORT综合征的儿童在生长激素治疗期间出现胰岛素抵抗性糖尿病。

Insulin-resistant diabetes during growth hormone therapy in a child with SHORT syndrome.

作者信息

Verge C F, Donaghue K C, Williams P F, Cowell C T, Silink M

机构信息

Ray Williams Institute of Paediatric Endocrinology, Royal Alexandra Hospital for Children, Sydney, Australia.

出版信息

Acta Paediatr. 1994 Jul;83(7):786-8. doi: 10.1111/j.1651-2227.1994.tb13142.x.

DOI:10.1111/j.1651-2227.1994.tb13142.x
PMID:7949817
Abstract

We report the case of a 13-year-old boy with SHORT syndrome, including lipoatrophy and insulin resistance, who developed diabetes mellitus while receiving growth hormone therapy. The diabetes persisted after cessation of exogenous growth hormone but oral hypoglycaemic therapy was successful and could be discontinued eight months later.

摘要

我们报告了一例患有SHORT综合征(包括脂肪萎缩和胰岛素抵抗)的13岁男孩,他在接受生长激素治疗期间患上了糖尿病。停用外源性生长激素后,糖尿病仍持续存在,但口服降糖治疗取得成功,八个月后可停药。

相似文献

1
Insulin-resistant diabetes during growth hormone therapy in a child with SHORT syndrome.一名患有SHORT综合征的儿童在生长激素治疗期间出现胰岛素抵抗性糖尿病。
Acta Paediatr. 1994 Jul;83(7):786-8. doi: 10.1111/j.1651-2227.1994.tb13142.x.
2
Symptomatic non-insulin-dependent diabetes mellitus during therapy with recombinant human growth hormone.重组人生长激素治疗期间出现症状性非胰岛素依赖型糖尿病
J Pediatr. 1993 Oct;123(4):590-2. doi: 10.1016/s0022-3476(05)80959-x.
3
Insulin antagonistic effects of growth hormone in short children.生长激素对矮小儿童的胰岛素拮抗作用。
Horm Res. 1995;44(5):197-202. doi: 10.1159/000184625.
4
[Lipoatrophic diabetes with insulin resistance controlled by metformin].[二甲双胍控制胰岛素抵抗的脂肪萎缩性糖尿病]
Ann Dermatol Venereol. 1988;115(11):1151-2.
5
[Lipoatrophic diabetes with acanthosis nigricans. Prolonged blood glucose normalization by continuous infusion of insulin].[伴有黑棘皮病的脂肪萎缩性糖尿病。通过持续输注胰岛素实现血糖长期正常化]
Presse Med. 1984 Apr 14;13(16):987-9.
6
Carbohydrate metabolism during growth hormone treatment and after discontinuation of growth hormone treatment in girls with Turner syndrome treated with once or twice daily growth hormone injections.特纳综合征女孩每日注射一次或两次生长激素治疗期间及停止生长激素治疗后的碳水化合物代谢
Clin Endocrinol (Oxf). 2000 Jun;52(6):741-7. doi: 10.1046/j.1365-2265.2000.01007.x.
7
Assessing insulin resistance: application of a fasting glucose to insulin ratio in growth hormone-treated children.评估胰岛素抵抗:空腹血糖与胰岛素比值在生长激素治疗儿童中的应用。
Horm Res. 2002;57(1-2):37-42. doi: 10.1159/000057945.
8
Insulin resistant diabetes mellitus in SHORT syndrome: case report and literature review.SHORT 综合征伴胰岛素抵抗性糖尿病:病例报告及文献复习。
Endocr J. 2021 Jan 28;68(1):111-117. doi: 10.1507/endocrj.EJ20-0291. Epub 2020 Sep 3.
9
Insulin sensitivity decreases in short children born small for gestational age treated with growth hormone.
J Pediatr. 2009 Apr;154(4):509-13. doi: 10.1016/j.jpeds.2008.09.050. Epub 2008 Nov 28.
10
Lipoatrophic diabetes mellitus treated by continuous subcutaneous insulin infusion.
Diabetes Metab. 1998 Dec;24(6):544-6.

引用本文的文献

1
Identification of A Novel Mutation of SHORT Syndrome: A Case Report.SHORT综合征新突变的鉴定:一例报告
Clin Case Rep. 2025 Aug 25;13(9):e70820. doi: 10.1002/ccr3.70820. eCollection 2025 Sep.
2
SHORT Syndrome: an Update on Pathogenesis and Clinical Spectrum.SHORT综合征:发病机制与临床谱的最新进展
Curr Diab Rep. 2022 Dec;22(12):571-577. doi: 10.1007/s11892-022-01495-8. Epub 2022 Nov 19.
3
The first SHORT syndrome in a Taiwanese boy: A case report and review of the literature.台湾一名男孩首例SHORT综合征:病例报告及文献复习
Mol Genet Metab Rep. 2021 May 7;27:100768. doi: 10.1016/j.ymgmr.2021.100768. eCollection 2021 Jun.
4
SHORT syndrome in two Chinese girls: A case report and review of the literature.两名中国女孩的SHORT 综合征:病例报告及文献复习。
Mol Genet Genomic Med. 2020 Sep;8(9):e1385. doi: 10.1002/mgg3.1385. Epub 2020 Jun 29.
5
Metformin paradoxically worsens insulin resistance in SHORT syndrome.二甲双胍在短综合征中反常地恶化胰岛素抵抗。
Diabetol Metab Syndr. 2019 Oct 1;11:81. doi: 10.1186/s13098-019-0477-z. eCollection 2019.
6
Mutation of Paternal Gene Causing Silver-Russell Syndrome in a Sporadic Patient.父源基因的突变导致一例散发型Silver-Russell综合征患者发病。
Front Genet. 2017 Aug 8;8:105. doi: 10.3389/fgene.2017.00105. eCollection 2017.
7
Diagnosis and management of Silver-Russell syndrome: first international consensus statement.Silver-Russell 综合征的诊断和管理:首个国际共识声明。
Nat Rev Endocrinol. 2017 Feb;13(2):105-124. doi: 10.1038/nrendo.2016.138. Epub 2016 Sep 2.