Botero D, Danon M, Brown R S
Department of Pediatrics, University of Massachusetts Medical School, Worcester 01655.
J Pediatr. 1993 Oct;123(4):590-2. doi: 10.1016/s0022-3476(05)80959-x.
In a 12-year-old girl, hyperglycemia and an elevated glycohemoglobin concentration developed after therapy with growth hormone for familial short stature. Both clinical and biochemical abnormalities disappeared after therapy was discontinued. The insulin response to an oral glucose tolerance test was abnormal 3 months after discontinuation of growth hormone; 18 months later, it remained delayed but was normal quantitatively.
一名12岁女孩因家族性身材矮小接受生长激素治疗后出现高血糖和糖化血红蛋白浓度升高。停止治疗后,临床和生化异常均消失。停止生长激素治疗3个月后,口服葡萄糖耐量试验的胰岛素反应异常;18个月后,反应仍延迟,但数量上正常。