Diamond L W, Mishka V G, Seal A H, Nguyen D T
Pathology Institute, University of Cologne, Germany.
Proc Annu Symp Comput Appl Med Care. 1994:298-302.
A clinical database was designed as part of a comprehensive workstation for diagnostic laboratory hematology. The database stores coded findings pertinent to hematologic disorders including inherited abnormalities, previous surgery, malignancies, current therapy, and laboratory test results. The workstation includes knowledge-based systems for peripheral blood analysis, flow cytometry studies, and bone marrow morphology. The peripheral blood system renders an interpretive report based on data from a complete blood count with manual review of a blood smear by a technologist. The flow cytometry module interprets the immunophenotyping and DNA content results, and correlates them with the clinical findings and the peripheral blood data. The bone marrow system bases its report on all of the available information including the morphologic review of the bone marrow specimen by a physician, the peripheral blood data, immunophenotype, and clinical/laboratory findings. Before generating an interpretive report, each of the knowledge-based systems automatically searches the clinical database for specific information pertinent to the findings in the case. Since the workstation must function in situations where access to distributed databases is not feasible or not yet practical, a data entry module with a graphical user interface has been created.
一个临床数据库被设计为诊断实验室血液学综合工作站的一部分。该数据库存储与血液系统疾病相关的编码结果，包括遗传性异常、既往手术、恶性肿瘤、当前治疗以及实验室检查结果。该工作站包括用于外周血分析、流式细胞术研究和骨髓形态学分析的基于知识的系统。外周血系统根据全血细胞计数数据生成解释性报告，并由技术人员手动复查血涂片。流式细胞术模块解释免疫表型和DNA含量结果，并将它们与临床发现和外周血数据相关联。骨髓系统的报告基于所有可用信息，包括医生对骨髓标本的形态学复查、外周血数据、免疫表型以及临床/实验室检查结果。在生成解释性报告之前，每个基于知识的系统都会自动在临床数据库中搜索与该病例的检查结果相关的特定信息。由于该工作站必须在无法访问分布式数据库或分布式数据库尚未实用的情况下运行，因此创建了一个带有图形用户界面的数据录入模块。
