Asare A L, Huda H, Klimczak J C, Caldwell C W
Department of Health Management & Informatics, University of Missouri-Columbia, School of Medicine, USA.
Proc AMIA Symp. 1998:952-6.
Studies have shown that monitoring HIV-infected patients undergoing antiretroviral therapy is best represented by combined measurement of plasma HIV-1 RNA and CD4+ T-lymphocytes [1]. This pilot study at the University of Missouri-Columbia integrates molecular diagnostic and flow cytometric data reporting to provide current and historical HIV-1 RNA levels and CD4+ T-cell counts. The development of a single database for storage and retrieval of these values facilitates composite report generation that includes longitudinal HIV-1 RNA levels and CD4+ T-cell counts for all patients. Results are displayed in tables and plotted graphically within a web browser. This method of data presentation converts individual data points to more useful medical information and could provide clinicians with decision support for improved monitoring of HIV patients undergoing antiretroviral therapy.
研究表明，对接受抗逆转录病毒治疗的HIV感染患者进行监测，最好通过联合检测血浆HIV-1 RNA和CD4+ T淋巴细胞来实现[1]。密苏里大学哥伦比亚分校的这项初步研究整合了分子诊断和流式细胞术数据报告，以提供当前和历史的HIV-1 RNA水平及CD4+ T细胞计数。开发一个用于存储和检索这些数值的单一数据库，有助于生成包含所有患者纵向HIV-1 RNA水平和CD4+ T细胞计数的综合报告。结果以表格形式显示，并在网络浏览器中以图形方式绘制。这种数据呈现方法将单个数据点转化为更有用的医学信息，并可为临床医生在改善对接受抗逆转录病毒治疗的HIV患者的监测方面提供决策支持。
