Sun Y, Kohane I, Stark A R
Children's Hospital, Harvard Medical School, Boston, MA.
Proc Annu Symp Comput Appl Med Care. 1994:757-61.
The control of oxygen delivery to mechanically ventilated newborn infants is a time intensive process that must balance adequate tissue oxygenation against possible toxic effects of oxygen exposure. Investigation in computer assisted control of mechanical ventilation is increasing, although very few studies involve newborn infants. We have implemented a fuzzy controller for the adjustment of inspired oxygen concentration (FIO2) in ventilated newborns. The controller utilizes rules produced by neonatologists, and operates in real-time. A clinical trial of this controller is currently taking place in the neonatal intensive care unit (NICU) of Children's Hospital, Boston, MA.
对机械通气新生儿的氧输送控制是一个耗时的过程,必须在保证足够的组织氧合与尽量减少氧暴露可能产生的毒性作用之间取得平衡。虽然涉及新生儿的研究很少,但对机械通气计算机辅助控制的研究正在增加。我们已实施一种模糊控制器,用于调节通气新生儿的吸入氧浓度(FIO2)。该控制器利用新生儿科医生制定的规则,并实时运行。目前,波士顿儿童医院新生儿重症监护病房(NICU)正在对该控制器进行临床试验。