Lu D C, Su Z J, Rui T
Affiliated Hospital of Zhenjiang Medical College.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 Mar;14(3):142-4, 131-2.
Effect of Jian Yan Ling (JYL, mainly consisted of Succinum, Pteria margaritifers and Astragalus membranaceus etc.) on serum lipids was studied by double-blind method in 128 hyperlipemia patients. Patients were divided randomly into two groups, the test groups (64 cases) treated with JYL, while the other 64 cases treated with placebo as control for 3 months. Serum total cholesterol (TC), triglyceride (TG), TC-high density lipolipid-cholesterol (TC-HDL-C), apoproteins were observed before and after treatment. Results showed that the TC, TG, apoproteins and lipoprotein-a of test group were all dropped significantly after JYL treatment (P < 0.01). The results suggested that JYL could regulate the blood lipids and could also exert an effect of antiatherosclerosis through reducing blood lipoprotein-a level. It is worth while to use JYL as an antihyperlipemic agent clinically.
采用双盲法对128例高脂血症患者研究了健延龄(JYL,主要由琥珀、珍珠母贝和黄芪等组成)对血脂的影响。患者随机分为两组,试验组(64例)服用JYL治疗,另外64例服用安慰剂作为对照,疗程3个月。观察治疗前后血清总胆固醇(TC)、甘油三酯(TG)、TC-高密度脂蛋白胆固醇(TC-HDL-C)、载脂蛋白。结果显示,JYL治疗后试验组的TC、TG、载脂蛋白和脂蛋白-a均显著下降(P<0.01)。结果提示,JYL可调节血脂,还可通过降低血液脂蛋白-a水平发挥抗动脉粥样硬化作用。临床上将JYL用作抗高脂血症药物是值得的。