Bao Z D, Wu Z G, Zheng F
Dept. of Geriatrics, Jinling Hospital, Nanjing.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1994 May;14(5):271-3, 259.
The protective effect on aminoglycoside nephrotoxicity by Cordyceps sinensis in the old patient was observed. 21 old patients were randomly divided into two groups. Each group received amikacin sulfate for 6 days. In addition, group A was administered Cordyceps sinensis for 7 days and group B was given placebo. The results revealed that group A developed less prominent nephrotoxicity compared with group B as evidenced by less urinary nephro-aminoglycosidase (NAGase) and beta-microglobulin in group A than those in Group B. These results suggested that Cordyceps sinensis exerted a protective effect on aminoglycoside nephrotoxicity in the old patients.
观察了冬虫夏草对老年患者氨基糖苷类肾毒性的保护作用。21例老年患者随机分为两组。每组接受硫酸阿米卡星治疗6天。此外，A组给予冬虫夏草7天，B组给予安慰剂。结果显示，与B组相比，A组的肾毒性不那么明显，表现为A组尿中肾氨基糖苷酶（NAGase）和β-微球蛋白低于B组。这些结果表明，冬虫夏草对老年患者氨基糖苷类肾毒性具有保护作用。
