Reinthaller A, Kainz C, Tempfer G, Joura E
Abteilung für Gynäkologie und Geburtshilfe, Universitätsklinik für Frauenheilkunde, Wien, Osterreich.
Gynakol Geburtshilfliche Rundsch. 1994;34(2):98-101. doi: 10.1159/000272345.
In the present study we present our experience and data with loop electrosurgical excision procedures for the treatment of human papilloma virus (HPV)-associated lesions and intraepithelial neoplasia of the cervix. 58 patients underwent loop excision because of colposcopically suspect cervical lesions. In 78 cases cone biopsy (large loop excision of the transformation zone, LLETZ + partial resection of the cervical canal) was performed. In 80% of the loop excisions the lesions were removed with clear resection margins. Patients undergoing LLETZ conization were compared to patients who had a cold knife conization previously. The two groups were matched with regard to age, parity and histology. The cone specimen of patients with LLETZ conization revealed lesion-free margins in 93% compared to 87% in the group with cold knife conization. Operation time and duration of hospital stay were significantly shorter in the group of LLETZ conization. Loop electrosurgical excision procedures therefore represent an adequate method for the treatment of HPV-associated lesions and intraepithelial neoplasia of the cervix.
在本研究中，我们展示了使用环形电外科切除手术治疗人乳头瘤病毒（HPV）相关病变及宫颈上皮内瘤变的经验和数据。58例患者因阴道镜检查怀疑宫颈病变而接受环形切除。78例进行了锥形活检（转化区大环形切除，即LLETZ + 宫颈管部分切除术）。在80%的环形切除术中，病变切除边缘清晰。将接受LLETZ锥形切除术的患者与先前接受冷刀锥形切除术的患者进行比较。两组在年龄、产次和组织学方面相匹配。LLETZ锥形切除术患者的锥形标本显示切缘无病变的比例为93%，而冷刀锥形切除术组为87%。LLETZ锥形切除术组的手术时间和住院时间明显更短。因此，环形电外科切除手术是治疗HPV相关病变及宫颈上皮内瘤变的一种合适方法。
