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骨髓毒性化疗所致中性粒细胞减少症的经济学研究

Economic study of neutropenia induced by myelotoxic chemotherapy.

作者信息

Montero M C, Valdivia M L, Carvajal E, Montaño A, Buenestado C, Lluch A, Atienza M

机构信息

Servicio de Farmacia, Hospital Universitario Virgen del Rocío, Sevilla, Spain.

出版信息

Pharm World Sci. 1994 Aug 5;16(4):187-92. doi: 10.1007/BF01872867.

DOI:10.1007/BF01872867
PMID:7951132
Abstract

This article describes the economic and social impact of neutropenia induced by myelotoxic chemotherapy in patients with cancer during the period 1 January-31 December 1991. Neutropenia is a life-threatening complication of chemotherapy in patients with cancer. The episodes of fever and infections originating from neutropenia require hospitalization of the patient until the granulocyte levels are restored. The calculation of the economic cost was based on the following parameters: length of stay in hospital, analytical tests performed on the patient, type and cost of drug therapy administered, blood transfusions performed, health assistance received, cost of isolation and absence from work. The overall economic cost of neutropenia in patients with cancer reached 329,775 pesetas ($2,893). Cost of the health-care staff was the largest budget item in relation to the total health resources estimated.

摘要

本文描述了1991年1月1日至12月31日期间癌症患者骨髓毒性化疗所致中性粒细胞减少症的经济和社会影响。中性粒细胞减少症是癌症患者化疗的一种危及生命的并发症。由中性粒细胞减少症引发的发热和感染发作需要患者住院,直到粒细胞水平恢复。经济成本的计算基于以下参数:住院时间、对患者进行的分析测试、所给予药物治疗的类型和成本、输血情况、获得的医疗援助、隔离成本以及旷工成本。癌症患者中性粒细胞减少症的总体经济成本达到329,775比塞塔(2,893美元)。与估计的总卫生资源相关,医护人员成本是最大的预算项目。

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Filgrastim. A reappraisal of pharmacoeconomic considerations in the prophylaxis and treatment of chemotherapy-induced neutropenia.

本文引用的文献

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Recombinant granulocyte colony-stimulating factor (rG-CSF): pharmacoeconomic considerations in chemotherapy-induced neutropenia.重组粒细胞集落刺激因子(rG-CSF):化疗所致中性粒细胞减少症的药物经济学考量
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The importance of dose and dose intensity in lung cancer chemotherapy.剂量和剂量强度在肺癌化疗中的重要性。
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Infectious disease management of adult leukemic patients undergoing chemotherapy: 1982 to 1986 experience at Stanford University Hospital.接受化疗的成年白血病患者的传染病管理:斯坦福大学医院1982年至1986年的经验
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The use of granulocyte colony-stimulating factor to increase the intensity of treatment with doxorubicin in patients with advanced breast and ovarian cancer.在晚期乳腺癌和卵巢癌患者中使用粒细胞集落刺激因子以增加阿霉素的治疗强度。
Br J Cancer. 1989 Jul;60(1):121-5. doi: 10.1038/bjc.1989.234.
9
Effect of the prospective-pricing system on drug use in Pennsylvania long-term-care facilities.前瞻性定价系统对宾夕法尼亚州长期护理机构药品使用的影响。
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